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Currently there is no evidence that it causes medullary thyroid cancer or affects MEN2 in humans ( Exp Diabetes Res

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Zepbound was FDA-approved in 2023 for long-term weight management in adults with obesity (with a body mass index of 30 or higher) and overweight (with a body mass index of 27 or higher) with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol

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Adipose natural regulatory B cells negatively control adipose tissue inflammation